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Shigeru Matsuura Selected Research

5- chloro- 2- (3- (4- phenyl- 3,6- dihydro- 1(2H)- pyridinyl)propyl)- 4(3H)- quinazolinone

8/2004A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia.

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Shigeru Matsuura Research Topics

Disease

3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
09/2011 - 08/2004
2Infarction (Infarctions)
09/2011 - 05/2011
2Cerebral Infarction
09/2011 - 05/2011
2Stroke (Strokes)
05/2011 - 08/2004
2Brain Ischemia (Cerebral Ischemia)
05/2011 - 08/2004
2Neurodegenerative Diseases (Neurodegenerative Disease)
09/2004 - 08/2004
1Ischemic Stroke
09/2011
1Ischemia
05/2011
1Parkinson Disease (Parkinson's Disease)
09/2004
1Brain Injuries (Brain Injury)
08/2004

Drug/Important Bio-Agent (IBA)

3Poly (ADP-Ribose) Polymerase-1IBA
09/2011 - 08/2004
2MP 124IBA
09/2011 - 05/2011
2NAD (NADH)IBA
05/2011 - 08/2004
2Neuroprotective AgentsIBA
05/2011 - 09/2004
12- (4- chlorophenyl)- 5- quinoxalinecarboxamideIBA
09/2004
1Poly(ADP-ribose) Polymerase InhibitorsIBA
09/2004
1QuinazolinonesIBA
08/2004
15- chloro- 2- (3- (4- phenyl- 3,6- dihydro- 1(2H)- pyridinyl)propyl)- 4(3H)- quinazolinoneIBA
08/2004
1Adenosine Diphosphate (ADP)IBA
08/2004
1EnzymesIBA
08/2004
1Reactive Oxygen Species (Oxygen Radicals)IBA
08/2004